Package: aSPU
Version: 1.50
Date: 2021-6-28
Title: Adaptive Sum of Powered Score Test
Description: R codes for the (adaptive) Sum of Powered Score ('SPU' and
        'aSPU') tests, inverse variance weighted Sum of Powered score
        ('SPUw' and 'aSPUw') tests and gene-based and some pathway
        based association tests (Pathway based Sum of Powered Score
        tests ('SPUpath'), adaptive 'SPUpath' ('aSPUpath') test,
        'GEEaSPU' test for multiple traits - single 'SNP' (single
        nucleotide polymorphism) association in generalized estimation
        equations, 'MTaSPUs' test for multiple traits - single 'SNP'
        association with Genome Wide Association Studies ('GWAS')
        summary statistics, Gene-based Association Test that uses an
        extended 'Simes' procedure ('GATES'), Hybrid Set-based Test
        ('HYST') and extended version of 'GATES' test for pathway-based
        association testing ('GATES-Simes'). ). The tests can be used
        with genetic and other data sets with covariates. The response
        variable is binary or quantitative. Summary; (1) Single
        trait-'SNP' set association with individual-level data ('aSPU',
        'aSPUw', 'aSPUr'), (2) Single trait-'SNP' set association with
        summary statistics ('aSPUs'), (3) Single trait-pathway
        association with individual-level data ('aSPUpath'), (4) Single
        trait-pathway association with summary statistics
        ('aSPUsPath'), (5) Multiple traits-single 'SNP' association
        with individual-level data ('GEEaSPU'), (6) Multiple traits-
        single 'SNP' association with summary statistics ('MTaSPUs'),
        (7) Multiple traits-'SNP' set association with summary
        statistics('MTaSPUsSet'), (8) Multiple traits-pathway
        association with summary statistics('MTaSPUsSetPath').
Author: Il-Youp Kwak and others (See Author(s) in each function manual)
Maintainer: Il-Youp Kwak <ikwak2@cau.ac.kr>
VignetteBuilder: knitr
Suggests: rmarkdown, markdown, knitr
Depends: R(>= 3.6.0), gee, MASS, mvtnorm, fields, matrixStats
License: GPL-3
URL: https://github.com/ikwak2/aSPU
RoxygenNote: 7.1.0
Repository: https://ikwak2.r-universe.dev
Date/Publication: 2021-06-28 16:38:24 UTC
RemoteUrl: https://github.com/ikwak2/aspu
RemoteRef: HEAD
RemoteSha: 6d6fab02967d1b9f409426e6e9fa66e667a060de
NeedsCompilation: no
Packaged: 2026-07-03 08:16:14 UTC; root